General Information

  • ID:  hor002548
  • Uniprot ID:  A0A6I8TEZ7
  • Protein name:  NPLP-1-5
  • Gene name:  5565029
  • Organism:  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  NIASLARKYELP
  • Length:  12
  • Propeptide:  MGNFKMLLPPKLFLRILMLLFLIVHDASSQYTDGNRRLKPCELESLLRDLTYPEEGYEMHAAALRNQLRHILEREPTDGAYQSLDEYGSYENTGPYEDKRSYRSLLRDGATFGKRNLGSLARAGLLRTPSTDYLKRSIATLAKNGQLPASREPDSEEAASAGGWNDEKRNLASARASGYMLNGKRNIASLARKYELPGKRNIQSLLRTGMLPSIAPKRNMQSLARDNSLPHFAGAAAQESKRNIQTLVRDWNLPRQQSMAADNEKRNIQSLKNAQGQGGGSSSGGRKKRELYYDDETLDDSAPEILEPVYQSSPLDYEELMEAMNEAYTPYYNSPADNHLEQKRYLGSLARAGHLHRYHRFYKRAPMGSFDGLYGNDDDDDNGTGSDNYEGEDRHKRKHASKDVLDDDNDDDDDNDEDYEPRSSVALHIPQKRHLGSIIRSGWMPSFRPSRTTGRFSRSGRARSSFTPNPSDYDNLSPAFVDDATALATAADFEQHQQQQQHPLPSAAGELPVYSPRGVLRHPELPHYTGAAFGNRPRMYAGGLPEEYLDSSSETSARPSNPFYTEDEFRCAARLRKLLYYLKKQYYLDNKYIQSVYGRNPVRY
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A6I8TEZ7-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002548_AF2.pdbhor002548_ESM.pdb

Physical Information

Mass: 157099 Formula: C62H103N17O18
Absent amino acids: CDFGHMQTVW Common amino acids: AL
pI: 9.3 Basic residues: 2
Polar residues: 3 Hydrophobic residues: 5
Hydrophobicity: -28.33 Boman Index: -1908
Half-Life: 1.4 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 114.17
Instability Index: 5555 Extinction Coefficient cystines: 1490
Absorbance 280nm: 135.45

Literature

  • PubMed ID:  20163154
  • Title:  Neuropeptidomics of the Mosquito Aedes Aegypti